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Injury risk posture

To gain insight into what NASA’s injury risk posture should be, it is helpful to review other industries and their respective risk postures derived from their contextual operational scenarios based upon scientific evidence gathered therein.

For the automotive industry, specifically passenger cars, most injury limits are based on a 5–50% risk of an abbreviated injury scale (AIS) 3+ injury, which delineates the occurrence of a severe injury (Association for the Advancement of Automotive Medicine, 2005). Although this seems like an objectionable risk posture, there are two main reasons that this posture is acceptable for the automotive industry. First, these limits are based on standardized tests that represent a worst case scenario, and not a “representative” collision. Second, the overall probability of a person being in a crash any time he or she gets into a vehicle is very remote (1 in 120,000) for passenger vehicle usage (National Highway Traffic Safety Administration, 2007, 2009). Therefore, after considering the severity of the collision and the probability of actually having a collision, the total risk of injury to automobile drivers is very low.

For military aircraft, the situation is similar, although more inherent risk is involved. Military aircraft (both fixed and rotary wing) are designed to allow for a higher risk posture than what is desired and acceptable for spacecraft occupants assigned to NASA. Again, these higher levels of risk are considered acceptable given that the overall risk of injury per “sortie” (defined as one deployment or dispatch – launch with subsequent landing – of a military aircraft on a mission) is 1 in 670 (or less), even though this is significantly higher than the risk seen in the operation of passenger cars (Mapes, 2006).

For NASA, the situation is very different. With passenger vehicles, millions of miles are driven each year with a relatively low risk of collision or injury. For the most part, passenger vehicle risk is constant during the entire trip or “sortie.” Similarly, for military aircraft, thousands of flight hours are logged with relatively low risks of injury, and like passenger vehicles, there is significant risk during the entire mission although this risk is a direct result of different variable causes (enemy fire, mechanical failures, weather, pilot errors, human factors, etc.). However, unlike passenger vehicles, military aircrews are subject to a higher risk of injury during takeoff and landing. This risk is closer to NASA’s environment where risk of injury due to dynamic loads is concentrated during launch and landing phases of operations when flight produces the highest loads on the vehicle. Unlike passenger vehicles and military aircraft, there is very low risk of injury due to impact once a stable orbit has been reached, due primarily to the fact that there are very small loads applied to the vehicle structure during this phase of flight. Additionally, the launch, launch abort, and landing environments for NASA are extreme in nature compared with what is nominally experienced during automobile driving or civilian/military flight. The differences between automotive, military, and NASA operational environments make it important to consider the overall acceptable probability of injury, given that occupants in a space vehicle will incur impact conditions every time the vehicle returns to Earth.

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Crew deconditioning

Several physiologic changes occur in response to microgravity. The two main changes concerning impact tolerance are bone mineral density loss and muscular tissue atrophy.

During prolonged spaceflight, skeletal density changes primarily in the lower extremities and spine (Lang et al., 2004) consistent with Wolff’s law (Wolff, 1986). Studies conducted using dual energy X-ray absorptiometry (DXA) have shown bone mineral density decreases on average of 1–1.6% in the spine, femoral neck, trochanter, and pelvis, with an average loss of 1.7% in the tibia after only 1 month in microgravity (LeBlanc et al., 1998; Vico et al., 2000). Because skeletal deconditioning is time dependent, any method for accommodating the losses will be mission length specific.

Changes in muscle mass and strength also occur, and are dependent on the exercise regime employed during spaceflight. During Skylab missions, leg volume decreased by 7–10% (Thornton and Rummel, 1977) and up to 19% in crewmembers aboard the Mir space station (Stein, 1999; LeBlanc et al., 2000). The muscle loss experienced by crewmembers is also selective; muscle fiber size in the vastus lateralis decreased after 5–11 days in flight at different rates. Edgerton et al. (1995) and Zhou et al. (1995) found decreases of 16% in Type I, 23% in Type IIa, and 36% in Type IIb fibers. In terms of muscle strength during 6 month missions, astronauts experienced muscle strength loss up to 24% at the knee and up to 22% in the ankle (Gopalakrishnan et al., 2010).

It is currently unclear how these changes affect human physiology and impact tolerance in the setting of spaceflight and landing following long duration mission profiles. However, it is fairly evident that greater OP measures will be needed for deconditioned crewmembers. Currently, these effects are accounted for by applying lower dynamic load limits, which are based on NASA’s Integrated Medical Model (Lewandowski et al., 2008). The Integrated Medical Model of bone loss is derived from bone mineral density changes, not on actual measured and scientifically validated human impact tolerance in these conditions. This approach may be acceptable for short stays on the international space station (ISS), but may not apply to or protect against the deleterious physiological effects of longer-duration missions to near-Earth objects, the moon, and/or Mars, since there is little known about spaceflight deconditioning beyond 6 months to 1 year. In addition, inflight countermeasures are being developed to counteract these physiological changes, so in the future, lowering the response limits may not be necessary.

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SlotsWise Verdict

Even though more features could have been included, the Power of Thor Megaways is an exciting game. Thanks to the Megaways engine, we enjoyed a dynamic experience with tumbles and consecutive wins. Moreover, the Free Spins round and the Hammer feature can also deliver great fun and some lucrative outcomes. You can check it out first-hand to see how fun it can be.

Current NASA Standards

Currently, NASA standards for transient accelerations (≤0.5 s) are based primarily on the Brinkley dynamic response criterion (BDRC) (National Aeronautics and Space Administration, 2011). The BDRC is a simple, lumped-parameter, and single degree of freedom model that estimates the whole body response due to applied acceleration, and is computationally efficient and requires very little in terms of validation testing.

However, the BDRC has limitations (Somers et al., 2013). It only predicts ranges of injury risk and cannot provide information as to the severity or anatomical location of an injury. Only the +Z axis injury risk is well validated (with operational ejection seat data); the ±X, ±Y, and −Z injury risk levels are statistically limited (Brinkley, 1985). In addition, these data do not account for the interactions between crewmembers, suit, and seat. The seat and helmet used in the human testing and development of the BDRC are very different from what is actually planned for MPCV. Previously performed tests did not typically include a suit, so suit interactions are not accounted for in the injury risk prediction.

Given the limitations of the current NASA Standards, the human research program (HRP) and the NASA Engineering and Safety Center (NESC) began studying alternatives for inclusion in the standard. This standard update work is primarily focused on the Orion vehicle.

Theme & Design

While Thor may be an angrier and older version of the one we are used to here – the game itself has a fairly pleasant theme and backdrop. The graphics are top-notch, as you would come to expect from Pragmatic Play, with a beautiful Asgardian field providing a surprisingly serene backdrop to all of the chaos and fun that takes place on the reels.

Those familiar with Norse mythology will recognize plenty of the symbols and imagery present in this game. An older and more aggressive-looking Thor is the central character who appears, as well as Freya, another Asgardian God. As well as this, several Viking side-kick-type characters make appearances. Of course, no Thor game would be complete without his iconic hammer, Mjolnir, making an appearance. This is one of the most valuable symbols that will appear in the game.

There are also some great animations on display here, with several of the gods coming to life and showing off their skills as you play. The slot also has a lively soundtrack which does a great job of getting you in the mood to play.

Overview

What players will really enjoy about the Power of Thor Megaways video slot is the padding that the selection of features add to your overall winnings. As if that wasn’t enough, the overall concept is utilized in a particularly smart way in this title, compared to it only being an afterthought like what players see in the majority of titles.

On top of that, as a part of this software company’s offering of games as a whole, this is a game that serves an important role since it is a good fit to many people. The gameplay in this video slot brings a serious amount of action, and we really enjoy how the visual appeal gives video slot fans an overwhelmingly immersive gameplay style compared to just being an unimportant detail.

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HOW TO PLAY GATES OF VALHALLA

The five-by-five grid that Gates of Valhalla is played on operates differently from your usual slot game. Instead of fixed win lines paying from left to right, you can win with three or more symbols across or vertically along any of the ten lines. So, there are five horizontal both-ways paylines and five vertical ones. In this slot, the maximum win is a staggering 10,000x the bet.

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Other Slots to Play If You Like Power of Thor Megaways Slot

The Viking theme is a popular one in slots and other games. Viking Voyage is another one to consider if you want more Viking goodness. This one, however, takes place on the seas aboard a boat.

One of the more exciting titles might be Sword of Khans. It has a Mongolian Warrior theme and features a similar mountain backdrop.

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Pragmatic Play has developed the Power of Thor Megaways slot using the latest technology. So you can play it on your smartphones like Androids, tablets, and iPhones.

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You can play the demo version of the Power of Thor Megaways without paying any real money.

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To reach the Gates of Valhalla, you had to be a noble warrior Viking, willing to go out with your sword to meet the steely embrace of the gods. In this Norse-themed slot from Pragmatic Play, you’ll meet Odin, Freya, and Thor along with Tumbling Reels, Roaming Wilds, and Free Spins. So, are you worthy of the gods?

ABOUT THE ROLE

Head of Quality and Regulatory

Your Main Functions:

The primary role of this position is to provide global leadership, direction and hands on  involvement regarding quality management system, quality control and quality  improvement process. This position requires strong product development and manufacturing knowhow in a regulated industry, customer and supplier relations, and a  thorough working knowledge of compliance requirements in an ISO 13485 environment.

Reporting to the Group CEO you are a hands-on leader responsible for:

o The setup, maintenance and auditing of the Group QMS according to ISO 13485, as well as the quality assurance over the product value chain for both company locations.

o Implement processes and procedures, and conduct analyses to sustain, improve, and harmonize QMS in alignment with customer, legal and regulatory requirements, as well as strategic direction.

o Establish and supervise adequate quality assurance and inspection processes and function at our development and production plants in the US and in CH and act as the Quality Manager of the US legal entity.

o Ensure seamless integration of the QMS throughout the business, while collaborating with individual process owners towards continuous improvements.

o Manage a small global quality team across both Swiss and US sites, and implement a performance and customer oriented, collaborative and team spirited agile culture. Empower the team members for independent, self-motivated thinking and actions.

o Manage and further develop the capabilities in the quality team and improve the technical, methodical and interpersonal skills of each team member.

o Lead and execute group training for all employees on quality management processes.

o Successfully manage, lead and/or support supplier, customer, and regulatory and internal audits, while meeting internal quality targets and commitments.

o Support process owners to establish and manage actionable key performance indicators and improve management reporting, information flow and business forecasting.

o Establish and maintain an external partner network for support of regulatory standards and compliance.

o Knowledge of and ability to lead the application of quality principles and tools (APQP, PPAP, AQL sampling, control plans, FMEA, statistical tools, verification & validation[1]IQ,OQ,PQ) across the organization.

Your Profile:

o Bachelor or Master in Engineering, Science and/or technical field

o +10 years of experience in Quality, and/or combined Quality management roles, including 7+ years of proven experience in multi-site, ISO 13485 quality and regulatory environment

o Experience in product development, manufacturing and life cycle management

o Strong self-motivation combined with a high personal responsibility, degree of reliability, quality awareness and sense for pragmatic solutions

o Demanding and persistent, but supportive and team oriented

o Strong use of MS-Office Tools, Visio, Minitab, MS-Project

o Business fluent in English, German is an asset

o Experience with FDA, IVDR, IVDD regulated medical devices, preferred

o Ability to travel ~20% between the two sites, customers and suppliers

What we offer:

Independent and varied position with growth potential in a dynamic and international work environment. A highly motivated, collegial team and attractive employment conditions await you.

Important – for the first 12 months the client wants someone that will travel to the USA one week per month to spend time with x2 USA based Quality employees. They are somewhat junior so need they assistance. Some WFH options but ideally  they want someone onsite 4-5 days per week.

© 2022 Grant Thornton UK LLP - All rights reserved. “Grant Thornton” refers to the brand under which the Grant Thornton member firms provide assurance, tax and advisory services to their clients and/or refers to one or more member firms, as the context requires. Grant Thornton UK LLP is a member firm of Grant Thornton International Ltd (GTIL). GTIL and the member firms are not a worldwide partnership. GTIL and each member firm is a separate legal entity. Services are delivered by the member firms. GTIL does not provide services to clients. GTIL and its member firms are not agents of, and do not obligate, one another and are not liable for one another’s acts or omissions.

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